Inflammatory Bowel Disease (IBD) comprises two chronic diseases: Ulcerative Colitis (UC) and Cronh’s Disease.
Ulcerative Colitis is a long-term condition which involve large intestine and the ulcers will develop on the surface of mucus of colon.in this condition the inflammation is start from the rectum and lower colon. men and women are equally affected by this disease.
Crohn Disease is chronic condition that cause inflammation in part of digestive system from the mouth to the rectum. the most part of GI tract may affect by this condition is end part of the small intestine (ileum).
Mesatin® 500 is an extended release formulation of mesalazine, it is an aminosalicylate anti-inflammatory agent for gastrointestinal use.
Generic Name: Mesalazine
Brand Name: Intesa® / Mesatin®
Dosage Form: Capsule
Strength: 500 mg
Indication: induction of remission and for the treatment of adult patients
Mechanism of Action: The mechanism of action of mesalazine is not understood fully, but it may have topical anti-inflammatory effect on colonic epithelial cells.
with mildly to moderately active ulcerative colitis.
Dosing Per Day:
2–4 g (acute) daily in divided doses
1.5–4 g (maintenance) daily in divided doses
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